Jeffrey Chang
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R. Jeffrey Chang, M.D., Professor of Reproductive Medicine Director Division of Reproductive Endocrinology and Infertility Telephone: |
Education
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1961-65 |
University of Oregon, Eugene, Oregon (BA) |
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1965-69 |
University of Oregon Medical School, Portland, Oregon (MD) |
Postgraduate Training
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1969-70 |
Intern, Medicine, Barnes Hospital, St. Louis, Missouri |
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1970-74 |
Resident, Obstetrics and Gynecology, Harbor General Hospital, Torrance, California |
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1974-75 |
Postdoctoral Fellowship, Reproductive Endocrinology, Division of Reproductive Biology, Obstetrics and Gynecology, Harbor General Hospital, Torrance, California |
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1975-77 |
Postdoctoral Fellowship, Reproductive Endocrinology, Reproductive Endocrinology Center, Obstetrics and Gynecology, University of California Medical Center, San Francisco, CA |
Academic Appointments
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1977-86 |
Department of Obstetrics and Gynecology, UCLA School of Medicine, Los Angeles, California |
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1986-96 |
Department of Obstetrics and Gynecology, UCD School of Medicine, Davis, California |
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1987-96 |
Chair, Department of Obstetrics and Gynecology, UCD School of Medicine, Davis, California |
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1997- |
Department of Reproductive Medicine, UCSD School of Medicine, La Jolla, California |
Professional Certifications
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1970 |
National Board of Medical Examiners |
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1971 |
State of California Board of Medical Examiners (Lic#G20109) |
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1977 |
Diplomat of the American Board of Obstetrics and Gynecology |
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1980 |
Diplomat of the American Board of Obstetrics and Gynecology, Subspecialty of Reproductive Endocrinology |
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1994 |
American Board of Obstetrics and Gynecology, Recertification |
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1994 |
American Board of Obstetrics and Gynecology, Subspecialty of Reproductive Endocrinology, Recertification |
Professional Membership/Service
NIH Reproductive Biology Study Section Member 1989-1993, Chair 1989-1993;
NIH Physiological Sciences Review Section Administrative, Chair 1991-1993;
American Board of Obstetrics and Gynecology Examiner, Subspecialty Board (Reproductive Endocrinology) 1992-Present;
American College of Obstetricians and Gynecologists GYN Practice Committee Chair 1994-95,
Subcommittee on Reproductive Endocrinology Practice Chair 1991-93, 1997-99,
Document Review Panel on Gynecology Vice-Chair 2001-02,
ACOG Section I, District IX Chair 1993-96;
Pacifici Coast Reproductive Society President 1989-90;
Society of Reproductive Endocrinologyists President 1990-92;
Association of Professors of Gynecology and Obstetrics President 1994-95;
American Society from Reproductive Medicine President 1999-2000,
UCSD Medical Center Chief of Staff 2003-2005.
Selected Publications (From a Total of 170 Published or In Press; 1974 - Present)
Chang RJ, Mandel FP, Lu KH, Judd HL. Enhanced disparity of gonadotropin secretion by estrone in women with polycystic ovarian disease. J Clin Endocrinol Metab 54:490-494, 1982.
Chang RJ, Laufer LR, Meldrum DR, DeFazio J, Lu KH, Vale WW, Rivier JE, Judd HL. Steroid secretion in polycystic ovarian disease after ovarian suppression with a long-acting gonadotropin-releasing hormone agonist. J Clin Endocrinol Metab 56:897-903, 1983.
Chang RJ, Nakamura R, Judd HL, Kaplan SA. Insulin resistance in non-obese patients with polycystic ovarian disease. J Clin Endocrinol Metab 57:356-359, 1983.
Steingold K, de Ziegler D, Cedar M, Meldrum DR, Lu KH, Vale WW, Rivier JE, Judd HL, Chang RJ. Clinical and hormonal effects of chronic long-acting gonadotropin-releasing hormone agonist treatment in polycystic ovarian disease. J Clin Endocrinol Metab 65:773-778, 1987.
de Ziegler D, Steingold K, Cedars M, Lu KH, Judd HL, Chang RJ. Recovery of hormone secretion after chronic gonadotropin-releasing hormone agonist administration in women with polycystic ovarian disease. J Clin Endocrinol Metab 68:1111-1117, 1989.
Erickson GF, Magoffin DA, Cragun JR, Chang RJ. The effect of insulin and insulin-like growth factors I and II on estradiol production by granulosa cells of polycystic ovaries. J Clin Endocrinol Metab 70:894-902, 1990.
Erickson GF, Magoffin DA, Garzo G, Cheung AP, Chang RJ. Granulosa cells of polycystic ovaries: are they normal or abnormal? Hum Reprod 7:293-299, 1992.
Cheung AP, Lu JKH, Chang RJ. Pulsatile gonadotropin secretion in women with polycystic ovary syndrome after gonadotropin-releasing hormone agonist treatment. Hum Reprod 12: 1156-1164, 1997.
Shimasaki S, Zachow RJ, Li D, Kim H, Iemura S, Ueno N, Sampath K, Chang RJ, Erickson GF. A functional bone morphogenetic protein system in the ovary. Proc Natl Acad Sci 96:7282-7287, 1999.
Chang RJ. Polycystic ovary syndrome: Diagnostic criteria. In Polycystic Ovary Syndrome: Basic Biology and Clinical Intervention (eds: Chang RJ, Dunaif A, Heindel J) Marcel Dekker, 2002
Coffler MS, Patel K, Dahan MH, Yoo RY, Malcom PJ, Chang RJ. Enhanced granulosa cell responsiveness to follicle stimulating hormone during insulin infusion in women with polycystic ovary syndrome treated with pioglitazone J Clin Endocrinol Metab 88:5624-5631, 2003.
Patel K, Coffler MS, Dahan MH, Yoo RY, Lawson MA, Malcom PJ, Chang RJ. Increased luteinizing hormone secretion in women with polycystic ovary syndrome is unaltered by prolonged insulin infusion. J Clin Endocrinol Metab 88:5456-5461, 2003.
Yoo RY, Dewan A, Basu R, Newfield R, Gottschalk M, Chang RJ. Increased luteinizing hormone pulse frequency in obese oligomenorrheic girls with no evidence of hyperandrogenism. Fertil Steril 85: 1049-56, 2006.
Wachs DS, Coffler MS, Malcom PJ, Shimasaki S, Chang RJ. Increased androgen response to follicle-stimulating hormone administration in women with polycystic ovary syndrome. J Clin Endocrinol Metab 93:1827-1833, 2008.