Professor Emeritus and Research Professor of Reproductive Medicine
Division of Perinatal Medicine

PhD in Physiology & Chemical Engineering
Michigan State University, 1973

telephone: 619 - 543 - 5255
Fax: 619 543 - 2919
e-mail: BobBrace@ucsd.edu

Teaching Interests: Fetal Physiology, Regulation of Fluid Balance, Statistical Analysis of Biological Data

General Research Area: Fetal Physiology & Fluid Balance

Specific Research Areas and Related Publications:

Recent Research Publications:

• Brace RA, Langendorfer C, Song TB, Mock DM. Red blood cell life span in the ovine fetus. Am J Physiol Regul Integr Comp Physiol 279(4); R1196-204, 2000.
  
  
• Chan TT, Richter PJ, Brace RA. Effect of laboratory acclimation on food and water consumption of pregnant sheep after fetal catheterization. Contemp Top Lab Anim Sci. 39(4):28-31, 2000.
  
  
• Matsumoto LC, Cheung CY, Brace RA. Effect of esophageal ligation on amniotic fluid volume and urinary flow rate in fetal sheep. Am J Obstet Gynecol. 182(3):699-705, 2000.
  
  
• Scheve EJ, Brace RA. Amniotic fluid volume responses to intra-amniotic infusion of lactate in fetal sheep. J Soc Gynecol Investig. 7(2):96-101, 2000.
  
  
• Brace RA, Ross MG. Physiology of Amniotic Fluid. In: UpToDate, Rose BD ed., UpToDate, Wellesley, MA, 2000.
  
  
• Bogic LV, Brace RA, Cheung CY. Developmental expression of vascular endothelial growth factor (VEGF) receptors and VEGF binding in ovine placenta and fetal membranes. Placenta 22(4):265-75, 2001.
  
  
• Hull AD, Brace RA. Erythrocyte and erythropoietin responses to hemorrhage in the immature and near term ovine fetus. Am J Obstet Gynecol. 185(2):501-6, 2001.
  
  
• Kim MJ, Bogic L, Cheung CY, Brace RA. Placental expression of erythropoietin mRNA, protein and receptor in sheep. Placenta 22(5):484-9, 2001.
  
  
• Kim MJ, Bogic L, Cheung CY, Brace RA. Expression of erythropoietin mRNA, protein and receptor in ovine fetal membranes. Placenta. 22(10):846-51, 2001.
  
  
• Matsumoto LC, Bogic L, Brace RA, Cheung CY. Fetal esophageal ligation induces expression of vascular endothelial growth factor messenger ribonucleic acid in fetal membranes. Am J Obstet Gynecol. 184(2):175-84, 2001.
  
  
• Matsumoto LC, Cheung CY, Brace RA. Increased urinary flow without development of polyhydramnios in response to prolonged hypoxia in the ovine fetus. Am J Obstet Gynecol. 184(5):1008-14, 2001.
  
  
• Ross MG, Brace RA. National Institute of Child Health and Development Workshop Participants. National Institute of Child Health and Development Conference summary: amniotic fluid biology--basic and clinical aspects. J Matern Fetal Med. 10(1):2-19. Review, 2001.
  
  
• Sohl BD, Cheung CY, Widness JA, Brace RA. Erythropoietin responses to progressive blood loss over 10 days in the ovine fetus. Am J Physiol Regul Integr Comp Physiol. 281(4):R1051-8, 2001.
  
  
• Wolf RB, Moise KJ Jr, Brace RA. Antibody-induced anemia in fetal sheep: model for hemolytic disease of the fetus and newborn. J Soc Gynecol Investig. 8(4):224-32, 2001.
  
  
• Ross MG, Brace RA and NIH Workshop Participants. National Institute of Child Health and Human Development Conference Summary: amniotic fluid biology basic and clinical aspects. J Matern Fetal Med 10: 219, 2001.
  
  
• Brace RA. Fluid Balance. In Fetal Growth and Development. Richard Harding and Alan D. Bocking, editors. Cambridge University Press, p. 94-113, 2001.
  
  
• Gagnon R, Harding R, Brace RA. Amniotic fluid and fetal urinary responses to severe placental insufficiency in sheep. Am J Obstet Gynecol. 186(5):1076-84, 2002.
  
  
• Kim SJ, Cheung CY, Widness JA, Brace RA. Temporal response of plasma erythropoietin to hemorrhage in the ovine fetus. J Soc Gynecol Investig. 9(2):75-9, 2002.
  
  
• Matsumoto LC, Bogic L, Brace RA, Cheung CY. Prolonged hypoxia upregulates vascular endothelial growth factor messenger RNA expression in ovine fetal membranes and placenta. Am J Obstet Gynecol. 186(2):303-10, 2002.
  
  
• Zhang L, Alexander RL, Widness JA, Cheung CY, Brace RA. Red cell mass responses to daily erythropoietin and iron injections in the ovine fetus. Am J Obstet Gynecol. 186(2):315-20, 2002.
  
  
• Brace RA. Fluid Distribution in the Fetus and Neonate. In: Fetal and Neonatal Physiology, 3rd edition. Polin R, Fox W, and Abman SH, editors. WB Saunders Co, Philadelphia, in press, 2002.
  
  
• Brace RA and Ross MG. Physiology of Amniotic Fluid. In: UpToDate, Rose BD ed, UpToDate, Wellesley, MA, 2002.
  
  
• Daneshmand SS, Cheung CY, Brace RA. Regulation of amniotic fluid volume by intramembranous absorption in sheep: role of passive permeability and vascular endothelial growth factor. Am J Obstet Gynecol. 188(3):786-93, 2003.
  
  
• Davis LE, Widness JA, Brace RA. Renal and placental secretion of erythropoietin during anemia or hypoxia in the ovine fetus. Am J Obstet Gynecol. 189(6):1764-70, 2003.
  
  
• Brace RA. Amniotic Fluid Dynamics. In: Maternal-Fetal Medicine: Principles and Practice, 5th edition. Chapter 3, p. 45-53. Creasy RK, and Resnik R, editors. Saunders, 2003.
  
  
• Brace RA. Fluid Distribution in the Fetus and Neonate. Chapter # 139 in Fetal and Neonatal Physiology, 3rd edition, ed Polin R, and Fox W, WB Saunders Co, Philadelphia, 2003.
  
  
• Thurlow RW, Brace RA. Swallowing, urine flow, and amniotic fluid volume responses to prolonged hypoxia in the ovine fetus. Am J Obstet Gynecol. 189(2):601-8, 2003.