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R. Jeffrey Chang, M.D.

 

Professor of Reproductive Medicine, Director/Division of Reproductive Endocrinology and Infertility.

 

 

Telephone: (858) 534-8930
Fax: (858) 534-8856
E-mail: rjchang@ucsd.edu


Education:

1961-65  

University of Oregon, Eugene, Oregon (BA)

1965-69  

University of Oregon Medical School,  Portland, Oregon (MD)

Postgraduate Training:

1969-70

Intern, Medicine,  Barnes Hospital, St. Louis, Missouri

1970-74

Resident, Obstetrics and GynecologyHarbor General Hospital, Torrance, California

1974-75

Postdoctoral Fellowship, Reproductive Endocrinology, Division of Reproductive Biology, Obstetrics and Gynecology, Harbor General Hospital, Torrance, California

1975-77

Postdoctoral Fellowship, Reproductive Endocrinology, Reproductive Endocrinology Center, Obstetrics and Gynecology, University of California Medical Center, San Francisco, CA


Academic Appointments:

1977-86 

Department of Obstetrics and Gynecology,  UCLA School of Medicine, Los Angeles, California

1986-96   

Department of Obstetrics and Gynecology,  UCD School of Medicine, Davis, California

1987-96 

Chair,  Department of Obstetrics and Gynecology,  UCD School of Medicine, Davis, California

1997- 

Department of Reproductive Medicine,  UCSD School of Medicine, La Jolla, California

Professional Certifications:

1970

National Board of Medical Examiners

1971

State of California Board of Medical Examiners (Lic#G20109)

1977

Diplomat of the American Board of Obstetrics and Gynecology

1980 

Diplomat of the American Board of Obstetrics and Gynecology,                     Subspecialty of Reproductive Endocrinology

1994 

American Board of Obstetrics and Gynecology, Recertification

1994  

American Board of Obstetrics and Gynecology, Subspecialty of                         Reproductive Endocrinology, Recertification

Professional Membership/Service:

NIH Reproductive Biology Study Section Member 1989-1993, Chair 1989-1993; NIH Physiological Sciences Review Section Administrative, Chair 1991-1993; American Board of Obstetrics and Gynecology Examiner, Subspecialty Board (Reproductive Endocrinology) 1992-Present; American College of Obstetricians and Gynecologists GYN Practice Committee Chair 1994-95, Subcommittee on Reproductive Endocrinology Practice Chair 1991-93, 1997-99, Document Review Panel on Gynecology Vice-Chair 2001-02, ACOG Section I, District IX Chair 1993-96; Pacifici Coast Reproductive Society President 1989-90; Society of Reproductive Endocrinologyists President 1990-92; Association of Professors of Gynecology and Obstetrics President 1994-95; American Society from Reproductive Medicine President 1999-2000.

Selected Publications (From a Total of 170 Published or In Press; 1974 - Present):

Chang RJ, Mandel FP, Lu KH, Judd HL.  Enhanced disparity of gonadotropin secretion by estrone in women with polycystic ovarian disease.  J Clin Endocrinol Metab  54:490-494, 1982.

Chang RJ, Mandel FP, Wolfsen AR, Judd HL.  Circulating levels of plasma adrenocorticotropin in polycystic ovary disease.  J Clin Endocrinol Metab  54:1265-1267, 1982.

Chang RJ, Laufer LR, Meldrum DR, DeFazio J, Lu KH, Vale WW, Rivier JE, Judd HL.  Steroid secretion in polycystic ovarian disease after ovarian suppression with a long-acting gonadotropin-releasing hormone agonist.  J Clin Endocrinol Metab  56:897-903, 1983.

Chang RJ, Nakamura R, Judd HL, Kaplan SA.  Insulin resistance in non-obese patients with polycystic ovarian disease.  J Clin Endocrinol Metab  57:356-359, 1983.

Chang RJ.  Ovarian steroid secretion in polycystic ovarian disease.  Sem Reprod Endocrinol  2:244-250, 1984.

Geffner ME, Kaplan SA, Bersch N, Golde DW, Landlaw EM, Chang RJ.  Persistence of insulin resistance in polycystic ovarian disease after inhibition of ovarian steroid secretion.  Fertil Steril  45:327-333, 1986.

Steingold K, de Ziegler D, Cedar M, Meldrum DR, Lu KH, Vale WW, Rivier JE, Judd HL, Chang RJ.  Clinical and hormonal effects of chronic long-acting gonadotropin-releasing hormone agonist treatment in polycystic ovarian disease.  J Clin Endocrinol Metab  65:773-778, 1987.

de Ziegler D, Steingold K, Cedars M, Lu KH, Judd HL, Chang RJ.  Recovery of hormone secretion after chronic gonadotropin-releasing hormone agonist administration in women with polycystic ovarian disease.  J Clin Endocrinol Metab  68:1111-1117, 1989.

Erickson GF, Magoffin DA, Cragun JR, Chang RJ. The effect of insulin and insulin-like growth factors I and II on estradiol production by granulosa cells of polycystic ovaries.  J Clin Endocrinol Metab 70:894-902, 1990.

Cedars MI, Steingold KA, de Ziegler D, Lapolt PS, Chang RJ, Judd HL. Long-term administration of gonadotropin-releasing hormone agonist and dexamethasone: assessment of the adrenal role in ovarian dysfunction.  Fertil Steril  57:495-500, 1992.

Erickson GF, Magoffin DA, Garzo G, Cheung AP, Chang RJ.  Granulosa cells of polycystic ovaries: are they normal or abnormal?  Hum Reprod  7:293-299, 1992.

Chang RJ, Cragun JR.  Surgical and medical treatment of polycystic ovary syndrome.  In A Dunaif, J Givens, G Merriam, F Haseltine (eds) Polycystic Ovary Syndrome.  Current Issues in Endocrinology and Metabolism Series, Blackwell Scientific Publications, Inc., 1992.

Cheung AP, Chang RJ. Pituitary responsiveness to gonadotropin-releasing hormone agonist stimulation: a dose-response comparison of LH/FSH secretion in women with polycystic ovary syndrome and normal women.  Hum Reprod  10:1054-1059, 1995.

Cheung AP, Lu JKH, Chang RJ.  Hypothalamic-pituitary dynamics in polycystic ovary syndrome.  In RJ Chang (ed) Polycystic Ovary Syndrome, Springer-Verlag New York, Inc., 1996.

Chang RJ. Polyceptic ovary syndrome - diagnostic criteria.  In RJ Chang, JJ Weindel, A Dunaif (eds) Polycystic Ovary Syndrome Marcel Dekker New York, 2002.

 

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