Department of Reproductive Medicine
Obstetrics and Gynecology
Faculty_Wilkinson

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Department of Reproductive Medicine

Miles Wilkinson, PhD

Division of Reproductive Endocrinology and Infertility

 

Professor of Reproductive Medicine

 

  • PhD - University of Warwick, England, 1984
  • Postdoctoral Fellowship - Scripps Research Institute, 1984 - 1985
  • Postdoctoral Fellowship - University of California, San Diego, 1985 - 1987

 

Link to Dr Wilkinson's lab

Contact Information:

 

 

Email: mfwilkinson@ucsd.edu

 

Administrative Assistant:

  • Christina Bennett - 858.246.1345

 

Research Interest

Our studies are centered on the impact of gene regulatory circuits in normal development and disease. 

Our laboratory is interested in how transcriptional and post-transcriptional pathways impact normal development and how they are disrupted in disease. Our research interests overlap with the following fields:

  • RNA
  • Stem cell biology
  • Epigenetics
  • Reproductive biology
  • Developmental biology
  • Neurobiology 
  • Cancer

 

Honors/Awards

  • University of California, Regents Scholarship, 1976-1979

  • American Heart Association Scholarship, 1979  
  • U.K. Foreign Student Scholarship, 1981-1984    

  • NIH Training Grant Postdoctoral Fellow, 1984-1987 
  • Graduate School of Biological Science Dean’s Excellence Award, 1996-2000  
  • Outstanding Original Research Award for the best paper published in Journal of Andrology, 1999 
  • John P. McGovern Award for Outstanding Teaching (nominated; not awarded), 2000     
  • Amgen Award for Basic Science Research Presentation: “A T-Cell Receptor RNA Surveillance Mechanism” (postdoctoral-trainee Jun Wang), 2001 
  • Amgen Award for Basic Science Research Presentation: “A Novel RNA Surveillance Mechanism” (postdoctoral-trainee Jun Wang), 2002        
  • M.D. Anderson Cancer Center Faculty Achievement Award in Basic Science, 2003    
  • Graduate School of Biological Science Dean’s Excellence Award, 2003       
  • Amgen Award for Basic Science Research Presentation: “A New Homeobox Gene Cluster on the X Chromosome” (postdoctoral-trainee James MacLean), 2003 
  • Graduate School of Biological Science, Commendation for service to the graduate school (e.g., teaching and graduate student committees), 2004   
  • Ruby E. Rutherford Distinguished Professorship (endowed chair), 2006        
  • M.D. Anderson Research Trust Award (5-year award), 2006     
  • M.D. Anderson Alumni and Faculty Association Award for Clinical/Translational Research: “The NMD RNA Surveillance Pathway” (predoctoral-trainee Rachid Karam), 2007  
  • Chair, MGB (Molecular Biology) NIH study section, 2010-2012  
  • UCSD, accelerated promotion (to Level IX Full Professor), 2015     

 

Recent Publications

  • RNA Decay, Evolution, and the Testis.  Jones SH, Wilkinson M. RNA Biol. 2016 Dec 02; 0. PMID: 27911186.
    View in: PubMed
  • The human RHOX gene cluster: target genes and functional analysis of gene variants in infertile men.  Borgmann J, Tüttelmann F, Dworniczak B, Röpke A, Song HW, Kliesch S, Wilkinson M, Laurentino S, Gromoll J. Hum Mol Genet. 2016 Nov 15; 25(22):4898-4910. PMID: 28171660.
    View in: PubMed
  • The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment. Song HW, Bettegowda A, Lake BB, Zhao AH, Skarbrevik D, Babajanian E, Sukhwani M, Shum EY, Phan MH, Plank TD, Richardson ME, Ramaiah M, Sridhar V, de Rooij DG, Orwig KE, Zhang K, Wilkinson M. Cell Rep. 2016 Sep 27; 17(1):149-64. PMID: 27681428.
    View in: PubMed
  • The nonsense-mediated RNA decay pathway is disrupted in inflammatory myofibroblastic tumors. Lu J, Plank TD, Su F, Shi X, Liu C, Ji Y, Li S, Huynh A, Shi C, Zhu B, Yang G, Wu Y, Wilkinson M, Lu Y. J Clin Invest. 2016 Aug 1; 126(8):3058-62. PMID: 27348585.
    View in: PubMed
  • Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate.  Lou CH, Dumdie J, Goetz A, Shum EY, Brafman D, Liao X, Mora-Castilla S, Ramaiah M, Cook-Andersen H, Laurent L, Wilkinson M. Stem Cell Reports. 2016 Jun 14; 6(6):844-57. PMID: 27304915.
    View in: PubMed

 

For a full list of publications click HERE